Combination Drug & Multi-Layer Tablet Formulation

Multi-Layer Tablet Formulation

There are many reasons for choosing a multi-layer tablet form over a more conventional mono-layer tablet. These can include the need to keep modified-release formulations separate from those that are immediately bio-available, aesthetic appeal, combination products and product line extension. The most common multi-layer dosage form is the bi-layer, followed by the tri-layer and up to four or more layers.

Pharmaceutical Manufacturing Capabilities in Many Forms

As a fully cGMP contract pharmaceutical manufacturing facility, CoreRx™ provides formulation development, analytical methods development, and clinical material resources, utilizing a variety of multi-layer tablet equipment. In addition to our multiple mono-layer capabilities, CoreRx can produce a variety of oral solid dosage forms, up to four layers, utilizing multi-layer press technology.

CoreRx brings together innovation & scientific expertise by combining our scientific know-how, industry experience, and commitment to quality. CoreRx has a proven track record for delivering innovative solutions, on-time, and on budget.

Advantages of Multi-Layer Tablet Technology

  • Create a competitive advantage
  • Improve patient compliance
  • Increase the life cycle of a product
  • Higher Drug Loading Capacity
  • Ability to release multiple APIs
  • Broad range of release profiles
  • Ability to separate incompatible APIs
  • Cost Saving by reducing manufacturing activities

Multi-Particulate Drug Delivery

  • There are many reasons for choosing a multi-particulate drug delivery form over a more conventional single unit delivery form.
  • To separate modified-release from immediate release actives
  • Increased bioavailability
  • Aesthetic appeal
  • New combination drug products
  • Product line extension

CoreRx employs a variety of equipment for the development and manufacture of multi-particulate combination drug products. Whether your need is for multiple tablets in a capsule, pellets, granules, nano-particles, co-processed spray dried powders or multiple powders in capsules, CoreRx has you covered.

However, equipment represents only the tools needed to get the job done. At CoreRx, the real asset is our people. Our senior scientists are personally involved in every aspect of your project. Not only does CoreRx have the expertise to handle your most complex formulations, we pride ourselves on unsurpassed communication, innovative problem solving, and overall dedication to meet your timelines & project expectations.

Advantages of Multi-Particulate Drug Delivery

  • Increase the life cycle of a product
  • Creates a competitive advantage
  • Improve patient compliance
  • Has all advantages of a single unit formulation
  • Ability to release multiple APIs
  • Allows a broad range of release profiles
  • Reduces unit to unit variation
  • Increases bioavailability of drugs
  • Overall unique, cost effective, dosage form

Discover The Benefits Of Working With CoreRx

  • Our scientists have expertise in a virtually every dosage form so you can rest assured we can quickly and effectively create solutions to formulation dilemmas.
  • Our staff has over 200 years of combined experience in contract pharmaceutical development giving us a unique insight and deep understanding of the process.
  • CoreRx is founded on effective communication and active client involvement which ensures your timelines and expectations are met again and again.
  • Our facilities and teams are designed to provide you the greatest flexibility while maintaining quality which means even as your project requirements change, our services can keep up with your needs.
  • We’re fast! CoreRx has the experience to identify the most effective process and keep your project on schedule throughout it. Without sacrificing quality, we’ll get your product through manufacturing and on the market quickly.

Call, email, or complete the form to learn more about the benefits of partnering with CoreRx for your pharmaceutical development project.

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