Equipment List

Formulation Development

Processing

Mixing

  • 2, 4, 8 and 16 qt. Patterson-Kelly (P-K) V-Blender
  • Turbula T2C Mixer
  • IKA Homogenizer T25 Ultra-Turrax
  • Stir-Pak Overhead Mixer
  • 50L 3d Bin Blender
  • Glass Reactor Vessel, Jacketed, 1L and 2L
  • LevTech Wand Mixer

Granulation/Drying

  • Vector Fluid Bed Granulators/Dryers with Top Spray Insert and Wurster Column
  • Vector High Shear Granulator
  • Spheronizer/Extruder
  • Glatt FM-VG-10M Mobile Vertical Granulator

Particle Sizing

  • Quadro Comil Model 197
  • Fluid Air Micronizer

Encapsulation

  • Dott Bonapace En-Cap Capsule Filler
    - Capsules
    - Multi-particulate capsules
    - Liquid in capsules
  • ProFil 100 Encapsulator (Manual Fill)

Tableting and Coating

  • Dynamic Rotary Tablet Press, 10 Station, Type B Tooling
  • Tri-Layer Tablet Press 27 stations
  • Bosch/Manesty Flexi-Tab Single Station Tri-Layer Tablet Press
  • Vector LDCS Tablet Coaters with 1.5L & 4L Perforated
    Pan Inserts
  • Carver Single Station Press
  • Korsch Minitab (R&B 6 Station - Fully Instrumented)

 

cGMP Manufacturing
Solids Processing

Mixing

  • 4, 8, and 16 qt. Patterson-Kelly V-Blenders
  • 1, 3, 5, 15, and 30 cu.ft. Cross-Flow V-Blenders

Granulation/Drying

  • Vector Fluid Bed Processor
  • Vector High Shear Granulator/Vacuum Dryer

Particle Size Reduction

  • Quadro Comil Model 197 (2)

Encapsulation

  • Capsugel Ultra 8 II
  • PAM Model MF-30/AL-90
  • Dott Bonapace In-Cap Capsule Filler
    - Capsules
    - Multi-particulate capsules
    - Liquid in capsules
  • IMA 40E High Speed Encapsulator
  • Key International Capsule polisher(s)
  • Schaefer Capsule Bander
  • ProFill Encapsulator (various sizes)

Tableting and Coating

  • Fette 1200 Tablet Press
  • VanKel Hardness Tester
  • Carver Single Station Auto Tablet Press
  • Globe Pharma Press, 10 Station, Type B Tooling
  • Key International Tablet Dedusters
  • Bosch Flexitab Tablet Press (Mono-layer, Bi-layer,
    and Tri-layer)
  • O’Hara Tablet Coating System (20” Pan)
  • Thomas 36" Coating Pan (w/ 19" & 36" pans)

Analytical and Preformulation

Liquid Chromatography

  • Shimadzu LC-2010 with UV/Vis, PDA, RID, Conductivity, ELSD Detectors
  • Shimadzu Prominence UFLC System
  • Shimadzu Nexera UHPLC

Gas Chromatography

  • Shimazu GC-2010
  • Gerstel Multipurpose Sampler (Headspace and Liquid Injection)

Data Collection/Management

  • Shimadzu Class-VP Chromatography Data System

 

Dissolution
(USP Apparatus I and Apparatus II)

  • Cetus Automatic Dissolution Station
  • VanKel VK7000 Dissolution Baths (USP Type 1 and 2)
    - VanKel VK8000 Autosampler
    - VanKel VK750D Heaters / Circulators
  • VanKel Bio-Dis Apparatus (USP Type 3)
  • Distek 2100C Dissolution Baths (USP Type 1 and 2)
    - Distek DS4300 Autosampler
    - Small Vessel Adapters

Particle Size Analysis

  • Cilas 1190 Laser Diffraction Particle Size Analyzer with Powder and Liquid Modules
  • Cilas Microscope Particle Morphology Analyzer
  • ATM Sonic Sifter

Additional Analytical Tools

  • Mettler Coulometric Karl Fischer Titrator
  • Advanced Instruments Model 3320 Osmometer
  • BrookField RV-DVIII+ Rheometer (with Small Sample Adapter, Core, & Plate)
  • Dumatherm Total N2 Analyzer

Download the Equipment List here.

In Process/Physical Testing

  • ATM Sonic Sifter
  • Brookfield Digital Rheometer
  • Brookfield Cone & Plate Digital Rheometer
  • Mettler Toledo Halogen Moisture Analyzer
  • Mitutoyo Thickness Gauges
  • Advanced Instruments Osmometer
  • VanKel Hardness Tester
  • VanKel Disintegration Tester
  • VanKel Friabilitator
  • VanKel Tap Density Tester
  • Clias 1180 Laser Diffraction Particle Size Analyzer with Powder and Liquid Modules
  • Clias Microscope Particle Morphology Analyzer

Transfer/Packaging

  • Baxa Repeater Pumps
  • Induction Sealer
  • Turbofil Precision Syringe Filling Pump
  • MasterFlex Peristaltic Pumps
  • Spring Torque Tester

Miscellaneous

  • Nuaire Laminar Flow Hood
  • FTS Dura-Stop Stoppering Tray Dryer Lyophilzer
  • Buchi Mini Spray Dryer B-290

 

 

Liquids/Semi-Solids Processing

Mixing

  • Feldmeir SS Tank (70L, Bottom Mix, Jacketed Kettle, Vacuum Capable)
  • Feldmeir SS Tank (75L, Top Mix, Jacketed Kettle, Vacuum Capable)
  • SS Tank (300L, Top Mix, Jacketed Kettle, Vacuum Capable)
  • Lightnin EV 1 Mixer
  • Silverson In-Line Homogenizer
  • Omni Macro Homogenizer
  • Hobart 60 qt. Planetary Mixer
  • ATMI Bag Mixing System
  • Vacuum Emulsifying System

Transfer

  • Single Piston Bottle Filler
  • MasterFlex Peristalic Pumps
  • Baxa Repeater Pumps
  • Chatham Liquids Filling Line (2 Head)
  • Turbo-Fil Syringe-Filling Line (Non-Sterile)

Finishing/Packaging

  • TurboFil Vers-40 Walking Beam Vial Filler
  • Cap Torque Testers
  • Tube Crimper/Sealer
  • Kirby Lester Tablet/Capsule Counter (2)
  • Lepel Induction Sealer (2)
  • SADE P4 Tablet/Capsule Checkweigher
  • SADE P2 Tablet/Capsule Chechweigher
  • 12-Lane Automated Solids Packaging Line
  • Semi-Automatic Tube Filler
  • Blister Packaging Machine
  • Tablet/Capsule Printer
  • Strip Pack Machine (Solids, Semi-Solids)

Powder Filling

  • Per-Fil Nano Powder Auger Filler
  • Mettler Quantos Powder Micro-Dosing System
  • IMA Zanasi 40F Encapsulator

Miscellaneous

  • Terra Universal Laminar Flow HEPA Hood
  • Clean-In-Place skid
  • Buchi/Julabo Refrigerated Chiller/Heating Unit (2)

Preformulation

  • Heraeus SunTest CPS+ and SunCool Temperature Controller
  • Dissection Scopes
  • Agiltron Raman Spectrometer
  • Shimadzu IRAffinity-1 FTIR
  • Shimadzu UV 1700 Spectrophotometer
  • Spectramax Plus UV-Vis Microplate Reader
  • Rigaku XRD (X-Ray Diffraction)

 

cGMP Stability Chambers

(ICH Conditions)

Walk-In

  • 5°C
  • 25°C/60% RH
  • 30°C/65% RH
  • 40°C/75% RH

Reach-In Chambers

  • Three Custom Conditions
  • Darwin Freeze/Thaw Chamber

cGMP Storage Refrigerators

  • Revco Ultima -20°C
  • Revco Ultima -50°C
  • Revco -80°C
  • Warehouse Refrigerator for QA Retains Storage 2-8°C
 

Discover The Benefits Of Working With CoreRx

  • Our scientists have expertise in a virtually every dosage form so you can rest assured we can quickly and effectively create solutions to formulation dilemmas.
  • Our staff has over 200 years of combined experience in contract pharmaceutical development giving us a unique insight and deep understanding of the process.
  • CoreRx is founded on effective communication and active client involvement which ensures your timelines and expectations are met again and again.
  • Our facilities and teams are designed to provide you the greatest flexibility while maintaining quality which means even as your project requirements change, our services can keep up with your needs.
  • We’re fast! CoreRx has the experience to identify the most effective process and keep your project on schedule throughout it. Without sacrificing quality, we’ll get your product through manufacturing and on the market quickly.

Call, email, or complete the form to learn more about the benefits of partnering with CoreRx for your pharmaceutical development project.

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