There are many reasons for choosing a multi-layer tablet form over a more conventional mono-layer tablet. These can include the need to keep modified-release formulations separate from those that are immediately bio-available, aesthetic appeal, combination products and product line extension. The most common multi-layer dosage form is the bi-layer, followed by the tri-layer and up to four or more layers.
Manufacturing Capabilities in Many Forms
As a fully cGMP contract facility, CoreRx™ provides formulation development, analytical, and clinical material resources, utilizing a variety of multi-layer tablet equipment. In addition to our multiple mono-layer capabilities, CoreRx™ can produce a variety of oral solid dosage forms, up to four layers, utilizing multi-layer press technology.
CoreRx™ brings together innovation & scientific expertise by combining our scientific know-how, industry experience, and commitment to quality. CoreRx has a proven track record for delivering innovative solutions, on-time, and on budget.
Advantages of Multi-Layer Tablet Technology
- Create a competitive advantage
- Improve patient compliance
- Increase the life cycle of a product
- Higher Drug Loading Capacity
- Ability to release multiple APIs
- Broad range of release profiles
- Ability to separate incompatible APIs
- Cost Saving by reducing manufacturing activities
Multi-Particulate Drug Delivery
- There are many reasons for choosing a multi-particulate drug delivery form over a more conventional single unit delivery form.
- To separate modified-release from immediate release actives
- Increased bioavailability
- Aesthetic appeal
- New combination drug products
- Product line extension
CoreRx™ employs a variety of equipment for the development and manufacture of multi-particulate combination drug products. Whether your need is for multiple tablets in a capsule, pellets, granules, nano-particles, co-processed spray dried powders or multiple powders in capsules, CoreRx™ has you covered.
However, equipment represents only the tools needed to get the job done. At CoreRx, the real asset is our people. Our senior scientists are personally involved in every aspect of your project. Not only does CoreRx have the expertise to handle your most complex formulations, we pride ourselves on unsurpassed communication, innovative problem solving, and overall dedication to meet your timelines & project expectations.
Advantages of Multi-Particulate Drug Delivery
- Increase the life cycle of a product
- Creates a competitive advantage
- Improve patient compliance
- Has all advantages of a single unit formulation
- Ability to release multiple APIs
- Allows a broad range of release profiles
- Reduces unit to unit variation
- Increases bioavailability of drugs
- Overall unique, cost effective, dosage form
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